15. Which methods can be used to change the expression of a wild-type gene?
(A) Small interference RNA
(B) Antisense RNA
(C) MicroRNA
(D) TALEN gene editing
(E) CRISPR/Cas9 editing

16.About chromatin, which is (are) CORRECT? (A) Genes at heterochromatin is usually silent (B) Telomeric genes are highly expressed (C) Histone tails are usually highly methylated (D) H3K4 is an active mark (E) X chromosome is inactivated by a long non-coding RNA

複選題17.About transcription, which is (are) CORRECT? (A) A transcriptional factor can bind to an enhancer which is far away from the promoter. (B) The TATA box is located at all promoters of RNA Pol II transcribed gene. (C) The TATA box is usually bound by a TATA box binding protein (D) Histone methylation opens chromatin (E) Histone acetylation opens chromatin

18. Which of the following factors is essential for mRNA maturation in eukaryotes? (A) TATA-box binding protein (B) Ribosome (C) 5'-capping complex (D) Splicesome (E) RNA pol II polymerase

19. Which of the following sequence has the highest melting temperature? (A) Ggattc cctagg (B) Ggaccc cctagg (C) Ggaaac cctagg (D) Ggattc tttagg (E) Ggattc aatagg

20. Which of the following pathways need helicase? (A) DNA replication (B) Homologous recombination (C) Gene transcription (D) RNA splicing (E) RNA editing

21. Which of following statements for nucleic acid is (are) TRUE: (A) C, T are Purines (B) There are three hydrogen bonds between CG pairing (C) During the process of free nucleotides becoming RNA, every single nucleotide added, two phosphate groups are released. (D) The higher the GC content, the lower the Tm value is. (E) RNA at neutral pH buffer (pH=7) has no charge

22. What the followings are True when one design a set of primer for cloning: (A) Introducing extra sequences that would give us a restriction site in primer can be added at either 5' or 3' end of primer (B) Annealing temperature should only consider the sequence that could based paired with the target gene (C) Only if a N-terminus protein tag has been introduced into vector backbone, one should consider whether introduced restriction sites in the primer result in frame shift in the final protein products (D) Length of primer can be as short as 5 nucleotides (E) As long as melting temperature reaches to the target temperature, nucleotide composition is not affect the primer efficiency

複選題23. Which of the following statements for mRNA is (are) TRUE: (A) Prior to 5' mRNA capping, there are three phosphate at 5' end of mRNA (B) Cap structure is dispensable for protein translation initiation in eukaryotic mRNA. (C) Poly（Ａ） tail of the mRNA is encoded in the DNA sequence (D) One eukaryotic mRNA corresponding to one gene whereas one prokaryotic mRNA containing multiple gens. (E) RNA splicing is one of the first discovered enzymatic reaction that can be catalyzed by Ribozyme.

複選題24. Which of the following statements is (are) TRUE: (A) tRNA are transcribed by RNA polymerase II (B) Pre r-RNA are transcribed by RNA polymerase I (C) mRNA are transcribed by RNA polymerase III (D) long noncoding RNA are transcribed by RNA polymerase III (E) microRNA precursors are transcribed by RNA polymerase II

複選題25.For the statements of various biological processes in different cell compartments, which statement is (are) TRUE (A) Nucleolus is located in the nucleus (B) rRNA are made in the cytoplasm (C) RNA synthesis takes place in the cytoplasm (D) DNA replication takes place in nucleolus (E) Mitochondria has its own DNA

115年 - [無官方正解]115 國立臺灣大學_ 碩士班招生考試試題：基礎分子生物學#137679

115年 - [無官方正解]115 國立臺灣大學_ 碩士班招生考試試題：基礎分子生物學B#137647

114年 - [非官方正解]114 國立台灣大學_碩士班招生考試試題：基礎分子生物學#126024

113年 - [非官方正解]113 國立臺灣大學_碩士班招生考試：基礎分子生物學#118909

112年 - [非官方正解]112台大 基礎分子生物學.pdf#118452

111年 - [非官方正解]111 國立臺灣大學_碩士班招生考試試題：基礎分子生物學#120877

110年 - [非官方正解]110 國立臺灣大學_碩士班招生考試_部分系所:基礎分子生物學#101968

109年 - [非官方正解]109 國立臺灣大學_碩士班招生考試 :基礎分子生物學#125739

108年 - [非官方正解]108 國立臺灣大學_碩士班招生考試：基礎分子生物學#125746

107年 - [非官方正解]107 國立臺灣大學_碩士班招生考試：基礎分子生物學#125774