3. What is the functional similarity between prokaryotic Sigma factors and eukaryotic Transcription Factors?
(A) Both possess the catalytic active site required for RNA synthesis.
(B) Both must cross the nuclear envelope to bind DNA and regulate gene expression.
(C) Both are primarily responsible for recognizing specific promoter sequences to recruit RNA polymerase.
(D) Both are permanent subunits of the polymerase complex that remain bound during elongation.
(E) Both possess helicase activity to continuously unwind the DNA double helix during transcription.

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