16. Which of the following statements about cellular respiration is correct?
(A) If oxygen is present, pyruvate will be converted to acetyl CoA in the mitochondrial matrix.
(B) Substrate phosphorylation occurs when protons pass through ATP synthase and combine with oxygen to make water.
(C) An H⁺ electrochemical gradient is formed so that the H⁺ concentration is lower in the intermembrane space than inside the matrix.
(D) Oxygen is an excellent final electron acceptor because of its low electronegativity.
(E) In prokaryotic cells, the electron transport system occurs in the mitochondria.

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