66.下列何者會促進thyroid-stimulating hormone分泌?
(A)metformin
(B)levodopa
(C)metoclopramide
(D)bexarotene
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統計: A(172), B(700), C(1390), D(1192), E(0) #2865504
統計: A(172), B(700), C(1390), D(1192), E(0) #2865504
詳解 (共 10 筆)
#5543918
彙整樓上大大
推5F(用理解的真的比較好記xdddd)
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#5413555
Ref: UpToDate DRUGS THAT AFFECT TSH SECRETION
Inhibition of thyroid hormone synthesis and/or release – thionamides, lithium, perchlorate, aminoglutethimide, thalidomide, and iodine and iodine-containing drugs including amiodarone, radiographic agents, expectorants (eg, guaifenesin), kelp tablets, potassium iodine solutions (SSKI), Betadine douches, topical antiseptics
Decreased absorption of T4 – cholestyramine, colestipol, colesevelam, aluminum hydroxide, calcium carbonate, sucralfate, iron sulfate, raloxifene, omeprazole, lansoprazole, and possibly other medications that impair acid secretion, sevelemer, lanthanum carbonate, and chromium; malabsorption syndromes can also diminish T4 absorption
Immune dysregulation – interferon alfa, interleukin-2, ipilimumab, alemtuzumab, pembrolizumab, nivolumab
Suppression of TSH – dopamine
Destructive thyroiditis – TKIs (eg, sunitinib, sorafenib); checkpoint inhibitors (eg, nivolumab, pembrolizumab, and ipilimumab)
Increased type 3 deiodination – TKIs (eg, sorafenib)
Increased T4 clearance and suppression of TSH – bexarotene
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4
#5568627
提供口訣
使TSH↑:Metoclopramide、Donperidon
[促進腹部的馬甲線,妹頭動茲動]
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